We all know Orgo 1 professors love stereoisomers. Consider the question A + B = C. Most professors expect you to fill in the question mark with all possible products and then indicate the major product(s), while other professors may provide you a potential C and then ask you if the statement is True or False.Read More
Whether you’re trying to accomplish a substitution or elimination in your synthetic scheme, there’s no getting around that a good leaving group must be involved. You’ll have a host of ways to introduce leaving groups by your final exam. Some reagents will invert chiral centers (e.g. SOCl2/pyridine, PBr3) in the process, and others won’t.Read More
So your professor says your Orgo 1 final will have a few synthesis problems. The good news: you’ve only learned a handful of reactions. Namely, you’ve learned how to manipulate alkenes and alkynes, and you know a little about radicals, substitution versus elimination, and the chemistry of alcohols, thiols, ethers, and epoxides. The bad news: well–there’s none to give. Managing synthesis problems in Orgo 1 is easy when you learn to look for red flags!Read More
Determining which of two molecules is more acidic is tricky if you haven’t yet organized those factors that influence acidity. The protocol is a method I learned from my mastermind Orgo 2 professor to keep these ideas in order when they come into conflict. Namely:
Size is more important than
Electronegativity, which is more important than
Resonance, which trumps the
Inductive Effect.Read More
Learning amino acid structures is a challenging part of biology and biochemistry coursework. Many students feel totally overwhelmed by the task. The best way to master this skill is lots of repetition (here is a link to a Sporcle quiz that may help you with the repetition part) but it can be helpful to have tricks and mnemonics to get you started. Below is a chart with some mnemonics and tricks that I have collected over the years-hopefully this will be a good jumping off point for your amino acid mastery!Read More
This month, Sandra breaks down Question #2 on the 2015 AP Chemistry exam. Read step by step instructions on how to solve this tricky question, and get tips on how to avoid getting tripped up on questions like this in the future!
Come on, it can't be that hard... can it? [image source: Hunger Games]
Chemistry is confusing enough with IUPAC nomenclature procedures to know, and the difference between E/Z and cis/trans alkene descriptions, and so many other new terms, models, units, and symbols. But the most common and important symbol in chemistry is the arrow.Read More
To simplify colligative properties, picture what is happening when you dissolve a salt in water. We know that increasing the concentration of ions has an effect on the boiling and freezing points of water. How do you remember which way?Read More
No…not that kind of retro.
People often dismiss organic chemistry as “all memorization”. I disagree – organic chemistry is just a series puzzles based on a few basic concepts (electronics, sterics, orbitals) that come together to answer almost any problem you might encounter on your homework or tests.Read More